Diseases that constrict the skeletal structure of the chest wall and the spine with its articulations may interfere with the functional capacity of the diaphragmatic pump, facilitating the development of respiratory insufficiency and failure. The present article discusses the response of the respiratory muscles to mechanical overload.
Following a brief examination of the force these muscles are required to exert in normal conditions, we review the pathophysiology of some characteristic alterations brought about by a) chest wall diseases such as kyphoscoliosis; b) other diseases involving the bony structure of the chest wall such as ankylosing spondylitis and pectus excavatum; and c) extreme obesity. Systemic disorders of a neuromuscular type will be dealt with in a different chapter of the series.
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Escrito por Alexandre Legrand, Emmanuelle Schneider, Pierre-Alain Gevenois, Andre De Troyer
Escrito por Jaqueline Sayumi Minagawa ; Érika Mourão Theodoro ; Camila Fernandes ; Cindy Lia Borges Cesarino Ferreira ; Camila Campos Guerra Hara ; Silvia Regina da Silvia Boschi , Rodrigo Souza Nilo de Araújo Aguiar ; Leandro Lazzareschi
Escrito por Tainá Pimentel Ferraz, Miriana Carvalho de Oliveira, Gabriel Gomes Maia, João Pedro Silva Teixeira de Carvalho, Thiago Klem Pereira, Marco Orsini.
